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Endocrine cell excitability opens the way to novel pharmacological intervention: example of the anterior pituitary cell
Authors:Jean-Didier Vincent  Lucy Anna Kukstas  Pierre-Marie Lledo
Affiliation:(1) Centre National de la Recherche Scientifique (C.N.R.S.), Gif-sur-Yvette, France
Abstract:Conclusion Excitability appears to be an important property of adenohypophyseal cells. The example ofthe lactotroph cell illustrates how the modification of membrane electrical properties can allowthe cell to adapt its functional characteristics to different physiological demands, which mayeven coexist in a contradictory manner in one animal. The amalgam of endocrine cell andnerve cell characteristics in one membrane makes the adenohypophyseal cell an ideal model forstudies in pharmacology and cellular toxicology.
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