Gene regulation: hacking the network on a sugar high |
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| Authors: | Ellis Tom Wang Xiao Collins James J |
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| Affiliation: | Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada. |
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| Abstract: | In a recent issue of Molecular Cell, Lee et al. (2008) demonstrate that the forkhead-associated (FHA) domain of Dun1, a Chk2-related kinase involved in DNA damage signaling, selectively binds a diphosphorylated motif found in its paralog and upstream regulator Rad53. |
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