Distribution of pore sizes in black lipid membranes treated with nystatin |
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Authors: | M Moreno-Bello M Bonilla-Marín C González-Beltrán |
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Affiliation: | Departamento de Física, Facultad de Ciencias, Universidad Nacional Autónoma de México, D.F. |
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Abstract: | Resistance changes were measured on artificial membranes made of oxidized cholesterol and treated with nystatin. The experimental data were smoothed and then fitted to a mixture of Gaussian functions using the maximum likelihood method; the best fit was to a mixture of four gaussians centered approximately at 4, 6, 9 and 12 molecules per pore, leading to the conclusion that these are the most likely pore sizes. |
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