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Anticancer effects of bioactive berry compounds |
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| Authors: | Florence Folmer Umesh Basavaraju Marcel Jaspars Georgina Hold Emad El-Omar Mario Dicato Marc Diederich |
| Institution: | 1. Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Fondation de Recherche Cancer et Sang, H?pital Kirchberg, 9 Rue Edward Steichen, 2540, Luxembourg, Luxembourg 2. Division of Applied Medicine, Institute of Medical Science, School of Medicine and Dentistry, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, Scotland, UK 3. Marine Biodiscovery Centre, Chemistry Department, School of Natural and Computing Sciences, University of Aberdeen, Aberdeen, AB24 3UE, Scotland, UK 4. Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul, 151-742, Republic of Korea |
| Abstract: | In the present review, we describe chemical and chemopreventive properties as well as health benefits of both extracts and bioactive compounds from various types of berries including small soft-fleshed edible berries and from berry-like fruits such as strawberries, raspberries, blackberries, blueberries, mulberries, currants, gooseberries, elderberries, açai berries, and pomegranates. In particular, we describe how berry-derided phytochemicals, including anthocyanidins, proanthocyanidins, flavonols, flavanols, stilbenoids, terpenoids, ellagitannins, and ellagic acid target oxidative and UV radiation stress-induced DNA damage, Helicobacter pilori infection, pro-inflammatory as well as the major cancer hallmarks. |
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