Sesquiterpenoids from Pilea cavaleriei subsp. crenata |
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| Authors: | Gui-Hua Tang Chang-Song Sun Chun-Lin Long Ma-Lin Li Yue-Hu Wang Min Luo Hong-Sheng Wang Ya-Na Shi |
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| Institution: | 1. Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China;2. Graduate University of Chinese Academy of Sciences, Beijing 100039, PR China;3. Kunming Medical College, Kunming 650031, Yunnan, PR China;4. College of Life and Environmental Sciences Minzu University of China, Beijing 100081, PR China;5. Yunnan Agricultural University, Kunming 650201, PR China;6. Henan Institute of Science and Technology, Xinxiang 453003, PR China |
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| Abstract: | Three new humulane-type sesquiterpenes, 8-O-(p-coumaroyl)-5β-hydroperoxy-1(10)E,4(15)-humuladien-8α-ol (1), 8-O-(3-nitro-p-coumaroyl)-1(10)E,4(15)-humuladien-5β,8α-diol (2) and 8-O-(p-coumaroyl)-1(10)E,4(5)E-humuladien-8-ol (3), and a new copaborneol derivative, 1-O-p-coumaroyl-copaborneol (4), have been isolated from the methanol extract of Pilea cavaleriei Lévl. subsp. crenata C. J. Chen. Their structures were elucidated using spectroscopic methods. Cytotoxic and antimicrobial activities of the isolated compounds were evaluated. |
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