Isoplatensimycin: Synthesis and biological evaluation |
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| Authors: | Ki Po Jang Chan Hyuk Kim Seong Wook Na Hiyoung Kim Heonjoong Kang Eun Lee |
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| Affiliation: | 1. Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-747, Republic of Korea;2. School of Earth and Environmental Sciences, College of Natural Sciences, Seoul National University, Seoul 151-747, Republic of Korea |
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| Abstract: | Isoplatensimycin, a novel analog of platensimycin, was synthesized via intramolecular dipolar cycloaddition of a carbonyl ylide. Isoplatensimycin showed little activities against strains of Staphylococcus aureus, but exhibited activities against some vancomycin-resistant enteroccoci. |
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