Evaluation of dihydrooroidin as an antifouling additive in marine paint |
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| Authors: | Christian Melander Peter DR Moeller T Eric Ballard Justin J Richards Robert W Huigens John Cavanagh |
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| Institution: | 1. Assistant professor of Obstetrics & Gynecology, Ain Shams University, Cairo, Eygpt;2. Professor of Diagnostic Radiology, Mansoura University, Egypt;3. Assistant professor of Clinical & Chemical Pathology, Fayoum University, Egypt;4. Al-Rashid Maternity Hospital, Kuwait;1. Department of Medicinal Chemistry, College of Pharmacy, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, USA;2. Institute of Wound Research, Department of Obstetrics and Gynecology, College of Medicine, University of Florida, Gainesville, FL 32610, USA |
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| Abstract: | Methods used to deter biofouling of underwater structures and marine vessels present a serious environmental issue and are both problematic and costly for government and commercial marine vessels worldwide. Current antifouling methods include compounds that are toxic to aquatic wildlife and marine ecosystems. Dihydrooroidin (DHO) was shown to completely inhibit Halomonas pacifica biofilms at 100 μM in a static biofilm inhibition assay giving precedence for the inhibition of other marine biofilm-forming organisms. Herein we present DHO as an effective paint-based, non-cytotoxic, antifouling agent against marine biofouling processes in a marine mesocosm. |
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