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Classification of hybrid and altered Vibrio cholerae strains by CTX prophage and RS1 element structure |
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| Authors: | Je Hee Lee Seon Young Choi Yoon-Seong Jeon Hye Ri Lee Eun Jin Kim Binh Minh Nguyen Nguyen Tran Hien M. Ansaruzzaman M. Sirajul Islam Nurul A. Bhuiyan S. K. Niyogi B.L. Sarkar G. Balakrish Nair Dae Shick Kim Anna Lena Lopez Cecil Czerkinsky John D. Clemens Jongsik Chun Dong Wook Kim |
| Affiliation: | 1. International Vaccine Institute, Seoul, 151-919, Republic of Korea 2. School of Biological Sciences, Seoul National University, Seoul, 151-747, Republic of Korea 3. National Institute of Hygiene and Epidemiology, Hanoi, 10,000, Vietnam 4. International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, 1212, Bangladesh 5. National Institute of Cholera and Enteric Diseases, Kolkata, 700 010, India 6. Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 135-710, Republic of Korea |
| Abstract: | Analysis of the CTX prophage and RS1 element in hybrid and altered Vibrio cholera O1 strains showed two classifiable groups. Group I strains contain a tandem repeat of classical CTX prophage on the small chromosome. Strains in this group either contain no element(s) or an additional CTX prophage or RS1 element(s) on the large chromosome. Group II strains harbor RS1 and CTX prophage, which has an E1 Tor type rstR and classical ctxB on the large chromosome. |
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