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The trypanosomal trans-sialidase: two catalytic functions associated with one catalytic site |
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| Authors: | Colman Peter M Smith Brian J |
| Affiliation: | Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria, Australia. |
| Abstract: | The structure of the trypanosomal trans-sialidase reveals a canonical sialidase catalytic site elaborated with a conformational switch that creates an adjacent binding pocket for lactose. |
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