| 增强子及其生物信息学预测 |
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| 引用本文： | 熊春江,江黎明.增强子及其生物信息学预测[J].生命的化学,2011(3). |
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| 作者姓名： | 熊春江 江黎明 |
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| 作者单位： | 广东医学院生物化学与分子生物学研究所; |
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| 摘 要： | 真核生物基因表达调控是当代分子生物学研究的重要课题之一。增强子是主要的真核生物基因表达调控的顺式作用元件,能有效促进基因表达。因此,增强子的相关研究是当今分子生物学研究的重点之一。运用生物信息学方法具有方便、快捷以及成本低等优势,这使得生物信息学成为当代分子生物学研究的重要工具。本文简单综述了增强子相关研究进展和采用生物信息学策略对序列保守性增强子进行预测和定位的几个常用数据库和具体方法。
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| 关 键 词： | 增强子 顺式调控元件 生物信息学 |
Research progress of enhancer and its bioinformatics prediction |
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| XIONG Chunjiang,JIANG Liming Institute of Biochemistry , Molecular Biology,Guangdong Medical College,Zhanjiang ,China.Research progress of enhancer and its bioinformatics prediction[J].Chemistry of Life,2011(3). |
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| Authors: | XIONG Chunjiang JIANG Liming Institute of Biochemistry Molecular Biology Guangdong Medical College Zhanjiang China |
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| Institution: | XIONG Chunjiang,JIANG Liming Institute of Biochemistry and Molecular Biology,Guangdong Medical College,Zhanjiang 524023,China |
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| Abstract: | The regulation of gene expression in eukaryotic is one of the most important issues in modern molecular biology research.Enhancer is a main cis-acting element of gene expression regulation in eukaryotes,which can effectively promote the gene expression.Therefore,enhancer-related research is one of the key piont in molecular biology.Bioinformatics has advantages of convenience,rapidness and cheapness,etc.,which makes it an important research tool in modern molecular biology.This paper briefly reviews the res... |
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| Keywords: | enhancer cis-regulatory element bioinformatics |
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