Plasma and erythrocyte magnesium, manganese, zinc, and plasma calcium levels in G-6-PD-deficient and normal male children |
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Authors: | Süreyya Bilmen Sarikçio?lu Saadet Gümü?lü Nimet Uysal T Aslan Aksu |
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Institution: | (1) Department of Biochemistry, Akdeniz University, Antalya, Turkey;(2) Department of Physiology, Faculty of Medicine, Akdeniz University, Antalya, Turkey |
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Abstract: | Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency is the most common human enzymopathy in the world. Trace elements are
important for normal hematopoiesis and can play a role in acute hemolytic anemia induced by G-6-PD deficiency. For this purpose,
we studied two groups consisting of 10 male children who are G-6-PD-deficient and 12 age-matched normal male children to compare
plasma and erythrocyte magnesium, manganese, zinc, and plasma calcium levels between G-6-PD-deficient and normal children.
All assays were performed under normal conditions free of any oxidative attack that may result in hemolytic crisis in G-6-PD-deficient
subjects. All parameters in each group did not differ significantly except for erythrocyte G-6-PD activities. These data show
that plasma and erythrocyte trace element contents of G-6-PD-deficient subjects do not differ in normal conditions. |
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Keywords: | G-6-PD deficiency plasma erythrocyte magnesium manganese zinc calcium |
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