WebCARMA: a web application for the functional and taxonomic classification of unassembled metagenomic reads |
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Authors: | Wolfgang Gerlach Sebastian Jünemann Felix Tille Alexander Goesmann and Jens Stoye |
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Institution: | (1) Faculty of Technology, Bielefeld University, Bielefeld, Germany;(2) Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany;(3) Department of Periodontology, University Hospital M?nster, M?nster, Germany |
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Abstract: | Background Metagenomics is a new field of research on natural microbial communities. High-throughput sequencing techniques like 454 or
Solexa-Illumina promise new possibilities as they are able to produce huge amounts of data in much shorter time and with less
efforts and costs than the traditional Sanger technique. But the data produced comes in even shorter reads (35-100 basepairs
with Illumina, 100-500 basepairs with 454-sequencing). CARMA is a new software pipeline for the characterisation of species
composition and the genetic potential of microbial samples using short, unassembled reads. |
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