Endogenous transmembrane tunnel formation mediated by phi X174 lysis protein E. |
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| Authors: | A Witte, G Wanner, U Bl si, G Halfmann, M Szostak, W Lubitz |
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| Affiliation: | Institute of Microbiology and Genetics, University of Vienna, Austria. |
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| Abstract: | Biochemical and genetic studies have suggested that a transmembrane tunnel structure penetrating the inner and outer membranes is formed during the lytic action of bacteriophage phi X174 protein E. In this study we directly visualized the lysis tunnel by using high-magnification scanning and transmission electron microscopy. |
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