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健康人和感染患者抗绿脓杆菌内毒素蛋白(EP)抗体水平的测定分析
引用本文:敬德仲,尤旭,曲杰,卢东升,常淑琴,王玉琪,苏华.健康人和感染患者抗绿脓杆菌内毒素蛋白(EP)抗体水平的测定分析[J].生物技术,1992(1).
作者姓名:敬德仲  尤旭  曲杰  卢东升  常淑琴  王玉琪  苏华
作者单位:黑龙江省科学院应用微生物研究所 哈尔滨 (敬德仲,尤旭,曲杰,卢东升),黑龙江省卫生防疫站免疫科 哈尔滨 (常淑琴,王玉琪),黑龙江省卫生防疫站免疫科 哈尔滨(苏华)
摘    要:用微量间接血凝法检测了健康人和绿脓杆菌感染患者血清抗EP抗体.健康人共检测154人.基础抗体水平绝大部分在1:8以下(占85.05%)EP—HA GMT为1:7.3.无性别差异(x~2=3.04、P>0.05).绿脓杆菌感染患者检测38例,免疫前GMT高于健康人1.43倍,免疫后较免疫前GMT提高4倍.绿脓杆菌EP是绿脓杆菌共同抗原,检查人抗EP抗体水平对诊断、防治绿脓杆菌感染具有重要临床意义.

关 键 词:绿脓杆菌  内毒素蛋白  EP抗体  平均几何滴度(GMT)

Assayand Analysis of Antibody Level of Anti-endotoxiN Protein of Pseudomonas Aeruginosa Between healthy Person and Patients
Jing de zhong You xu Qu jie Lu dong sheng,Institute of Applied Microbiogy Heilongjiang Academy of Sciences Immunology R esterch Labor ator y Harbin,Chan shu qin Wang yu qi Su hua.Assayand Analysis of Antibody Level of Anti-endotoxiN Protein of Pseudomonas Aeruginosa Between healthy Person and Patients[J].Biotechnology,1992(1).
Authors:Jing de zhong You xu Qu jie Lu dong sheng  Institute of Applied Microbiogy Heilongjiang Academy of Sciences Immunology R esterch Labor ator y Harbin  Chan shu qin Wang yu qi Su hua
Institution:Jing de zhong You xu Qu jie Lu dong sheng Institute of Applied Microbiogy Heilongjiang Academy of Sciences Immunology R esterch Labor ator y Harbin Chan shu qin Wang yu qi Su hua Department of Immunology of Anti-epidemic Station of Heilongjiang Province Harbin
Abstract:Antibody level of serum against Ep of healthy person and Patients infected Pseudomonas aeruginosa was analysed by a micro-passive hemag-glutination reaction in the artical Total healthy person 154 including 99 male and 55 female has been assayed Most part of basic antibody level is below 1:8 and 85.05% EP-HA GMT is 1:7.3 But it is not different between male and female (x2=3.04 P>0.05) a 37 Pseudomonas aeruginosa infected patients was assayed GMT is higher 1.43 fold (9.96/7.3) than healthy person before immunity and it is higher 4 fold (41.31/9.96) After immunity than before that The EP of pseadomonas aeruginosa is a common antigen of pseudomomas aeruginoa So to assay antibopy level of person serum against EP is very important for clinical diagnosis treatmant of infection of Pseudomonas aeruginosa.
Keywords:Pseudomonas aeruginosa  Endotoxin protein  EP Antibody  Geometric Mean titer (GMT)
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