Modification of fatty acid composition in tomato (Lycopersicon esculentum) by expression of a borage delta6-desaturase |
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| Authors: | Cook David Grierson Don Jones Craigh Wallace Andrew West Gill Tucker Greg |
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| Institution: | (1) School of Biosciences, Division of Nutritional Biochemistry, Loughborough, The University of Nottingham, LE12 5RD Leics;(2) School of Biosciences, Division of Plant Science, Loughborough, The University of Nottingham, LE12 5RD Leics |
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| Abstract: | The improvement of nutritional quality is one potential application for the genetic modification of plants. One possible target
for such manipulation is the modification of fatty acid metabolism. In this work, expression of a borage Δ6-desaturase cDNA in tomato (Lycopersicon esculentum L.) has been shown to produce γ-linolenic acid (GLA; 18:3 Δ6,9,12) and octadecatetraenoic acid (OTA; 18:4 Δ6,9,12,15) in transgenic leaf and fruit tissue. This genetic modification has also, unexpectedly, resulted in a reduction in the percentage
of linoleic acid (LA 18:2 Δ9,12) and a concomitant increase in the percentage of α-linolenic acid (ALA; 18:3 Δ9,12,15) in fruit tissue. These changes in fatty acid composition are thought to be beneficial for human health. |
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| Keywords: | Tomato fatty acids desaturase nutritional quality genetic modification |
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