Cell cycle: on-time delivery of Plk1 during cytokinesis |
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| Authors: | Rape Michael |
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| Affiliation: | Department of Molecular and Cell Biology, Division of Cell and Developmental Biology, University of California at Berkeley, Berkeley, CA 94720-3202, USA. mrape@calmail.berkeley.edu |
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| Abstract: | At anaphase, the kinase Plk1 localizes to the spindle midzone, where it orchestrates cytokinesis. New work has now identified PRC1 as a Plk1-delivery factor that is tightly controlled by opposing cyclin B-Cdk1- and Plk1-dependent phosphorylations. |
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