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A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting
Authors:Ximeng Han  Zhenqian Zhang  Lingjuan He  Huan Zhu  Yan Li  Wenjuan Pu  Maoying Han  Huan Zhao  Kuo Liu  Yi Li  Xiuzhen Huang  Mingjun Zhang  Hengwei Jin  Zan Lv  Juan Tang  Jinjin Wang  Ruilin Sun  Jian Fei  Bin Zhou
Institution:1. State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China;2. Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China;3. Shanghai Engineering Research Center for model organizations, Shanghai Model Organisms Center, Inc., Shanghai, China;4. Key Laboratory of Regenerative Medicine of Ministry of Education, College of Life Science and Technology, Jinan University, Guangzhou, China;5. Laboratory of Oral Microbiota and Systemic Diseases, Shanghai Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200125, China;6. National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai 200011, China;7. Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden;8. Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China;9. Department of Vascular Surgery, Xiamen Branch, Zhongshan Hospital, Fudan University, Xiamen, China;10. School of Life Science and Technology, ShanghaiTech University, 100 Haike Road, Shanghai 201210, China;11. School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China;12. Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China
Abstract:
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  • Keywords:intersectional genetics  lineage tracing  adipocyte progenitors  white adipocytes  lymphatic endothelial cells  Cre-loxP  Dre-rox  fate mapping
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