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Microbiota regulate innate immune signaling and protective immunity against cancer
Authors:Changsheng Xing  Mingjun Wang  Adebusola A. Ajibade  Peng Tan  Chuntang Fu  Lang Chen  Motao Zhu  Zhao-Zhe Hao  Junjun Chu  Xiao Yu  Bingnan Yin  Jiahui Zhu  Wan-Jou Shen  Tianhao Duan  Helen Y. Wang  Rong-Fu Wang
Affiliation:1. Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA;2. Norris Comprehensive Cancer Center, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA;3. Department of Pediatrics, Children’s Hospital Los Angeles, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90027, USA;4. Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030, USA;5. Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX 77030, USA;6. Department of General Surgery, Third Xiangya Hospital, XiangYa School of Medicine, Central South University, Changsha 410013, China;7. Jan and Dan Duncan Research Institute, Baylor College of Medicine, Houston, TX 77030, USA;8. State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, South East University, Nanjing 210096, China;9. Center for Infectious and Inflammatory Diseases, Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, TX 77030, USA
Abstract:
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  • Keywords:TAK1 signaling  acute colitis  colon cancer  microbiota  innate immunity  Th17 cells
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