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Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells
Authors:Yi Fang  Xiaojiang Xu  Jun Ding  Lu Yang  Mary T. Doan  Peer W.F. Karmaus  Nathaniel W. Snyder  Yingming Zhao  Jian-Liang Li  Xiaoling Li
Affiliation:1. Signal Transduction Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA;2. Integrative Bioinformatics Support Group, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA;3. Ben May Department for Cancer Research, The University of Chicago, Chicago, IL 60637, USA;4. Center for Metabolic Disease Research, Department of Microbiology and Immunology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA;5. Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Abstract:
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  • Keywords:metabolic switch  crotonylation  embryonic stem cells  endoderm differentiation  embryogenesis  epigenetics
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