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Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs
Authors:Kitra Cates  Matthew J. McCoy  Ji-Sun Kwon  Yangjian Liu  Daniel G. Abernathy  Bo Zhang  Shaopeng Liu  Paul Gontarz  Woo Kyung Kim  Shawei Chen  Wenjun Kong  Joshua N. Ho  Kyle F. Burbach  Harrison W. Gabel  Samantha A. Morris  Andrew S. Yoo
Affiliation:1. Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA;2. Center of Regenerative Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA;3. Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA;4. Department of Neuroscience, Washington University School of Medicine, St. Louis, MO 63110, USA;5. Program in Molecular Genetics and Genomics, Washington University School of Medicine, St. Louis, MO 63110, USA;6. Program in Developmental, Regenerative, and Stem Cell Biology, Washington University School of Medicine, St. Louis, MO 63110, USA;7. Program in Computational and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA
Abstract:
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  • Keywords:neuronal reprogramming  epigenetics  microRNA  single-cell RNA-sequencing  cell fate  direct conversion  non-coding RNA  chromatin regulation
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