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2,2-Dimethyl-4,5-diaryl-3(2H)furanone derivatives as selective cyclo-oxygenase-2 inhibitors |
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| Authors: | Shin S S Noh M S Byun Y J Choi J K Kim J Y Lim K M Ha J Y Kim J K Lee C H Chung S |
| Affiliation: | Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea. |
| Abstract: | A series of 2,2-dimethyl-5-[4-(methylsulfonyl)phenyl]-4-phenyl-3(2H)furanones was prepared and evaluated for their ability to inhibit cyclo-oxygenase-2 (COX-2). |
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