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The cysteinyl leukotriene receptors
Authors:Evans Jilly F
Affiliation:Pharmacology Department, Merck Research Laboratories, Merck & Co, Inc, 770 Sumneytown Pike, West Point, PA 19486, USA. jilly_evans@merck.com
Abstract:The cysteinyl leukotriene (CysLT) receptors are putative 7 transmembrane spanning G protein-coupled receptors (GPCRs) of the rhodopsin subfamily of GPCRs. Two human and mouse CysLT receptors have been molecularly cloned and characterized. The properties of these receptors agrees well with previous pharmacological CysLT agonist and antagonist characterizations of the CysLT receptors.
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