Advances in Nano Biotic/Abiotic Hybrid Systems: Protein-Based Engineered Devices |
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Authors: | Hyo-Jick Choi David Wendell Carlo D Montemagno |
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Institution: | (1) Department of Biomedical Engineering, University of Cincinnati, 2901 Woodside Drive, ML 0048, Cincinnati, OH 45221, USA |
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Abstract: | Integrative nanobiotechnology utilizes natural ideas and materials for manufacturing nanoscale devices. As living organisms
traditionally represent a good model for engineers to learn from, biological components of interest, with optimal functionality,
have been used in the creation of biotic/abiotic hybrid devices. As an example, bacteriorhodopsin/F0F1-ATP-synthase-incorporated polymer vesicles provide a model of hybrid protein/artificial synthetic membrane system to perform
biological functions. Some potential applications are the construction of intervesicular/intravesicular communications, such
as excitable vesicles (EVs), for biocomputer and biomolecular motor-powered nanoelectromechanical systems (NEMS) for nanomedicine.
Finally, advanced biotic/abiotic hybrid technology is expected to provide an alternative method to conventional fabrication
technology to meet the increasing demands by saving enormous engineering efforts. |
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Keywords: | nanobiotechnology biotic/abiotic polymer vesicles intervesicular/intravesicular communication excitable vesicle biocomputer nanoelectromechanical systems nanomedicine |
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