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A joint transcriptome-wide association study across multiple tissues identifies candidate breast cancer susceptibility genes
Affiliation:1. Department of Public Health Sciences, University of Chicago, Chicago, IL 60637, USA;2. Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, IL 60637, USA;3. Section of Hematology & Oncology, Department of Medicine, University of Chicago, Chicago, IL 60637, USA;1. Pacific Northwest Research Institute, Seattle, WA, USA;2. Department of Applied Mathematics, University of Washington, Seattle, WA, USA;3. Center for Genetic Medicine Research, Children’s National Research Institute, Children’s National Hospital, Washington, DC, USA;4. Department of Genomics and Precision Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC, USA;5. Department of Neurology, Division of Neurogenetics and Neurodevelopmental Disabilities, Children’s National Hospital, Washington, DC, USA;6. Center for Neuroscience Research, Children’s National Research Institute, Children’s National Hospital, Washington, DC, USA;1. The Center of Joint and Sports Medicine, Orthopedics Department, Zhongda Hospital, Southeast University, Nanjing, China;1. Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Carlton, VIC 3053, Australia;2. Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK;3. Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC 3168, Australia;4. Murdoch Children’s Research Institute, Royal Children’s Hospital, Parkville, VIC 3051, Australia;1. Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, Finland;2. Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA;3. Clinicum, Department of Public Health, University of Helsinki, Helsinki, Finland;4. Department of Epidemiology and Public Health, University College London, London, UK;5. Broad Institute of MIT and Harvard, Cambridge, MA, USA;6. Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA;1. The Dalglish Family 22q Clinic for Adults, and Department of Psychiatry, University Health Network, Toronto, ON, Canada;2. Toronto General Research Institute and Division of Cardiology, Department of Medicine, University Health Network, Toronto, ON, Canada;3. Clinical Genetics Research Program and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada;4. Department of Psychiatry, University of Toronto, Toronto, ON, Canada;5. 22q and You Center, Clinical Genetics Center, and Section of Genetic Counseling, Division of Human Genetics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA;6. Department of Pediatrics, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA;7. Department of Human Biology and Medical Genetics, Sapienza University, Rome, Italy;8. Advisium, ’s Heeren Loo Zorggroep, Amersfoort, the Netherlands;9. Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, the Netherlands;10. Department of Pediatric Rheumatology and Immunology, Queen Silvia Children’s Hospital, SahlgrenskaUniversity Hospital, Gothenburg, Sweden;11. Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden;12. Genetics & Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada;13. Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada;1. Rady Children’s Institute for Genomic Medicine, San Diego, CA 92123, USA;2. Rady Children’s Hospital, San Diego, CA 92123, USA;3. Keck Graduate Institute, Claremont, CA 91711, USA;4. Illumina, Inc., San Diego, CA 92122, USA;5. Alexion, Astra Zeneca Rare Disease, Boston, MA 02210, USA;6. Department of Pediatrics, University of California San Diego, San Diego, CA 92093, USA;7. Fabric Genomics, Inc., Oakland, CA 94612, USA;8. Mass General Brigham, Broad Institute, Ariadne Labs and Harvard Medical School, Boston, MA 02115, USA;9. Genomenon, Inc., Ann Arbor, MI 48108, USA;10. TileDB, Inc., Cambridge, MA 02142, USA;11. Luna PBC, Inc., San Diego, CA 92121, USA
Abstract:
Keywords:
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