A database for the provisional identification of species using only genotypes: web-based genome profiling |
| |
Authors: | Takehiro Watanabe Ayumu Saito Yusuke Takeuchi Mohammed Naimuddin Koichi Nishigaki |
| |
Affiliation: | (1) Department of Functional Materials Science, Saitama University, 255 Shimo-Okubo, 338-8570 Saitama, Saitama, Japan; |
| |
Abstract: | Background For a long time one could not imagine being able to identify species on the basis of genotype only as there were no technological means to do so. But conventional phenotype-based identification requires much effort and a high level of skill, making it almost impossible to analyze a huge number of organisms, as, for example, in microbe-related biological disciplines. Comparative analysis of 16S rRNA has been changing the situation, however. We report here an approach that will allow rapid and accurate phylogenetic comparison of any unknown strain to all known type strains, enabling tentative assignments of strains to species. The approach is based on two main technologies: genome profiling and Internet-based databases. |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|