Turnover of histone acetyl groups in cultured mammalian cells |
| |
Authors: | G R Shepherd B J Noland J M Hardin |
| |
Affiliation: | Biomedical Research Group, Los Alamos Scientific Laboratory, University of California, Los Alamos, New Mex. 87544, USA |
| |
Abstract: | The relative metobolic turnover rates of labeled histone fractions and of their labeled acetyl groups were determined in random cultures of exponentially-growing mammalian cells. Both the parent histones and their acetyl groups were conserved, neither exhibiting detectable metabolic turnover. The significance of these observations is discussed. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|