Ancient heat shock gene is dispensable. |
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| Authors: | J C Bardwell and E A Craig |
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| Institution: | Department of Physiological Chemistry, University of Wisconsin Medical School, Madison 53706. |
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| Abstract: | Hsp83 is a major eucaryotic heat shock protein and one of the most conserved proteins known. We have isolated an Escherichia coli gene homologous to eucaryotic Hsp83 and used it to construct a deletion mutation. The E. coli mutant was viable but had a slight growth disadvantage that increased with temperature. |
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