Association of thyroglobulin gene variants with carcass and meat quality traits in beef cattle |
| |
| Authors: | Guan-Yu Hou Zheng-Rong Yuan Han-Lin Zhou Lu-Pei Zhang Jun-Ya Li Xue Gao Dong-Jing Wang Hui-Jiang Gao Shang-Zhong Xu |
| |
| Affiliation: | (1) Institute of Tropical Crop Genetic Resources, Chinese Academy of Tropical Agricultural Sciences (CATAS), Danzhou Hainan, 571737, China;(2) Laboratory of Molecular Biology and Bovine Breeding, The Key Laboratory for Farm Animal Genetic Resources and Utilization of Ministry of Agriculture of China, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, 100193, China;(3) College of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi, 712100, China |
| |
| Abstract: | Thyroid hormones play an important role in regulating metabolism and can affect homeostasis of fat deposition. The gene encoding thyroglobulin (TG), producing the precursor for thyroid hormones, has been proposed as a positional and functional candidate gene for a QTL with an effect on fat deposition. In the present study, we identified 6 novel SNPs at the 3′ flanking region of the TG gene. The SNP marker association analysis indicated that the T354C, G392A, A430G and T433G SNP markers were significantly associated with marbling score (P < 0.05). Animals with the new homozygote genotype had higher marbling score than those with the other genotypes. Otherwise, the linkage disequilibrium analysis indicated that these four SNPs were completely linked (r 2 = 1). Results from this study suggest that TG gene-specific SNP may be a useful marker for meat quality traits in future marker assisted selection programs in beef cattle. |
| |
| Keywords: | |
| 本文献已被 PubMed SpringerLink 等数据库收录！ |
|
