Reversible Hypomagnesaemia-Induced Subacute Cerebellar Syndrome |
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Authors: | Saam Sedehizadeh Michael Keogh Adrian J Wills |
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Institution: | (1) Department of Neurology, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, NG7 2UH, UK;(2) Department of Neurology, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle Upon Tyne, UK |
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Abstract: | Magnesium is the second most abundant intracellular cation and is a fundamental cofactor in a multitude of cellular enzymatic
reactions. Magnesium deficiency causes diverse clinical features predominantly due to cardio- and neurotoxicity. We describe
a case of severe hypomagnesaemia associated with intermittent downbeat nystagmus, cerebellar ataxia, generalised convulsions
and a supraventricular tachycardia. On MRI imaging, a transient lesion of the cerebellar nodulus was observed, which has not,
to our knowledge, been previously described in isolated hypomagnesaemia. |
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Keywords: | |
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