| 一株银杏内生真菌菌株的抑菌活性成分研究 |
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| 引用本文： | 周松林,陈双林,谭光宏,王华,黄用豪,陈凡. 一株银杏内生真菌菌株的抑菌活性成分研究[J]. 天然产物研究与开发, 2010, 22(2) |
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| 作者姓名： | 周松林 陈双林 谭光宏 王华 黄用豪 陈凡 |
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| 作者单位： | 1. 海南医学院热带病重点实验室,海口,571101
2. 南京师范大学生命科学学院,南京,210046 |
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| 基金项目： | 国家自然科学基金，海南省自然科学基金 |
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| 摘 要： | 从银杏叶柄分离筛选到具抗菌活性的内生真菌Colletotrichum.SP NTB-2菌株,利用硅胶柱色谱、制备高效液相色谱等方法在其发酵产物中分离到抗枯草芽孢杆菌、鼠伤寒沙门氏菌等具有广谱抑菌活性的化合物,经MS、NMR等波谱数据确认该活性成分为芹菜素-8-C-葡萄糖苷(apigenin-8-C-β-D-glucopyranoside),该化合物首次从真菌中分离得到。
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| 关 键 词： | 内生真菌 银杏 芹菜素-8-C-葡萄糖苷 apigenin-8-C-β-D-glucopyranoside |
Antibacterial Substances of Endophytic Fungus Isolated from Ginkgo biloba |
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| ZHOU Song-lin,CHEN Shuang-lin,TAN Guang-hong,WANG Hua,HUANG Yong-hao,CHEN Fan. Antibacterial Substances of Endophytic Fungus Isolated from Ginkgo biloba[J]. Natural Product Research and Development, 2010, 22(2) |
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| Authors: | ZHOU Song-lin CHEN Shuang-lin TAN Guang-hong WANG Hua HUANG Yong-hao CHEN Fan |
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| Affiliation: | ZHOU Song-lin1,CHEN Shuang-lin2,TAN Guang-hong1,WANG Hua1,HUANG Yong-hao1,CHEN Fan11Hainan Provincial Key Laboratory of Tropical Medicine,Hainan Medical Collge,Haikou 571101,China,2Life Science College of Nanjing Normal University,Nanjing 210046 |
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| Abstract: | To study the antibacterial components from endophytic fungus strain,Colletotrichum.SP NTB-2 from Ginkgo biloba,silica gel column chromatography and pre-HPLC were used for the isolation and purification.A active compound was isolated from the fermentation broth of stains NTB-2 and identified as apigenin-8-C-beta-D-glucopyranoside on the basis of spectral data analysis. |
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| Keywords: | endophytic fungus Ginkgo biloba |
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