Long-Standing Undiagnosed Sheehan Syndrome Presenting as Polymorphic and Monomorphic Ventricular Tachycardia: A Case Series of 2 Patients |
| |
| Affiliation: | 1. Departments of Endocrinology, Instituto Português de Oncologia de Lisboa;2. Departments of Nuclear Medicine Department, Instituto Português de Oncologia de Lisboa;3. Departments of University Clinic of Endocrinology, Faculdade de Ciências Médicas, Universidade Nova de Lisboa.;1. Department of Clinical and Experimental Medicine, Section of Geriatrics, University of Parma, Italy;2. Geriatric Rehabilitation Department, University Hospital of Parma, Parma, Italy;3. Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania;4. Department of Psychiatry, VU University Medical Center/GGZ inGeest, Amsterdam, the Netherlands;5. National Institute on Aging, National Institutes of Health, Baltimore, Maryland.;1. Brain Tumor Center and Pituitary Disorders Program, John Wayne Cancer Institute at Saint John''s Health Center, Santa Monica, California;2. Department of Neurosurgery, UCLA Medical Center, Los Angeles, California;3. Teikyo University, Chiba, Medical Center, Chiba, Japan;4. Department of Medicine, UCLA School of Medicine, Los Angeles, California.;1. Department of Medicine, Division of Endocrinology & Metabolism;;2. Department of Medicine, Division of General Medicine Disciplines;;3. Department of Neurosurgery, Stanford University School of Medicine, Stanford, California.;1. Divisions of Endocrinology and General Surgery Departments of Medicine and Surgery, Rutgers Robert Wood Johnson Medical School;2. General Surgery, Departments of Medicine and Surgery, Rutgers Robert Wood Johnson Medical School,;3. Department of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey. |
| |
| Abstract: | ObjectiveTo describe 2 cases of Sheehan syndrome presenting with ventricular tachycardia.MethodsIn this case series, we present 2 cases of Sheehan syndrome presenting with ventricular tachycardia, which is an extremely rare complication of Sheehan syndrome. We review the literature for cases of panhypopituitarism presenting with ventricular tachycardia and also review the pathophysiologic mechanisms underlying development of ventricular tachycardia in these patients.ResultsTwo female patients presented with ventricular tachycardia. One patient had monomorphic and the other had polymorphic ventricular tachycardia. On further workup, both patients were found to have panhypopituitarism. Due to past history of postpartum hemorrhage, both patients were suspected of having Sheehan syndrome as the cause of panhypopituitarism. Electrocardiogram revealed prolonged QT interval. Both patients were started on hormone replacement therapy. Both patients responded well initially and were discharged home. One of the patients is alive and healthy at the time of this report. However, the other patient was readmitted with seizures a few days after discharge and unfortunately died of sudden cardiac arrest.ConclusionUntreated cases of Sheehan syndrome can present with fatal ventricular tachycardia. Hormone replacement in these patients can treat and prevent fatal arrhythmias. (Endocr Pract. 2014;20:e211-e214) |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
