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Human mesenchymal stromal cells primed with paclitaxel,apart from displaying anti-tumor activity,maintain their immune regulatory functions in vitro
Affiliation:1. Department of Pediatric Hematology/Oncology, IRCCS Bambino Gesù Children''s Hospital, Rome, Italy;2. University of Pavia, Pavia, Italy;3. Department of Biomedical, Surgical, Dental Sciences, University of Milan, Italy;4. UCV Neurobiology, IRCCS Neurological Institute, Carlo Besta, Milan, Italy;1. Department of Biology, Kharazmi University, Tehran, Iran;2. Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran;3. Department of Regenerative Medicine at the Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran;4. Urology and Nephrology Research Center, Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran;5. Department of Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran;6. Department of Veterinary Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran;7. Department of Clinical Sciences, Faculty of Veterinary Medicine, Karaj Branch, Islamic Azad University, Karaj, Iran;8. Department of Andrology at the Reproductive Biomedicine Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran;9. Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Tehran University of Medical Sciences, Tehran, Iran;10. Department of Genetics and Molecular Biology, Isfahan University of Medical Sciences, Isfahan, Iran;11. Department of Developmental Biology, University of Science and Culture, ACECR, Tehran, Iran;1. Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, 11361 – 87 Avenue, Edmonton, Alberta T6G 2E1, Canada;2. Food Bio-Nano Research Group, Korea Food Research Institute, 516, Baekhyun-Dong, Bundang-Ku, Seongnam-Si, Gyeonggi-Do 463-746, Republic of Korea;3. Center for Nutraceutical and Pharmaceutical Materials, Myongji University, Cheoin-gu, Yongin, Gyeonggi-Do 449-728, Republic of Korea;1. Hematology Service, Internal Medicine Department, Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México;2. Neuropediatrics Department, Hospital Universitario “Dr. José Eleuterio González,” Universidad Autónoma de Nuevo León, Monterrey, México;3. Radiology and Imaging Department, Hospital Universitario “Dr. José Eleuterio González,” Universidad Autónoma de Nuevo León, Monterrey, México;4. Universidad Autónoma de Madrid, Madrid, Spain;1. Medical Biochemistry Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt;2. Histology and Cell Biology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt;3. Clinical Pharmacology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt;4. Anesthesia and Intensive Care Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt;5. Microbiology and Immunology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Abstract:
Keywords:anti-tumor effect  immune modulatory properties  mesenchymal stromal cells  paclitaxel
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