Draft genome sequences of three NDM-1-producing Enterobacteriaceae
species isolated from Brazil |
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| Authors: | Polyana Silva Pereira Rodolpho Mattos Albano Marise Dutra Asensi Ana Paula D’Alincourt Carvalho-Assef |
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| Affiliation: | 1.Laboratório de Pesquisa em Infecção Hospitalar, Instituto Oswaldo Cruz-Fiocruz, Rio de Janeiro, RJ, Brasil;2.Departamento de Bioquímica, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil |
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| Abstract: | The emergence of multidrug-resistant Enterobacteriaceae strains producingcarbapenemases, such as NDM-1, has become a major public health issue due to a highdissemination capacity and limited treatment options. Here we describe the draftgenome of three NDM-1-producing isolates: Providencia rettgeri(CCBH11880), Enterobacter hormaechei subsp. oharae(CCBH10892) and Klebsiella pneumoniae (CCBH13327), isolated inBrazil. Besides blaNDM-1, resistance genes toaminoglycosides [aadA1, aadA2,aac(6’)-Ib-cr] and quinolones (qnrA1,qnrB4) were observed which contributed to the multidrugresistance profile. The element ISAba125 was found associated to theblaNDM-1 gene in all strains. |
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| Keywords: | NDM-1 Brazil Enterobacteriaceae |
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