The immune response of wild rainbow trout, Salmo gairdneri Richardson, to naturally acquired plerocercoid infections of Diphyllobothrium dendriticum (Nitzsch, 1824) and D. ditremum (Creplin, 1825) |
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Authors: | G. J. E. Sharp A. W. Pike C. J. Secombes |
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Affiliation: | Department of Zoology, University of Aberdeen, Tillydrone Avenue, Aberdeen, AB9 2TN, U.K. |
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Abstract: | Natural infections of rainbow trout with two species of Diphyllobothrium result in a host inflammatory response encapsulating the plerocercoid. The encapsulating cyst, observed by light and electron microscopy, comprises leucocytes, fibroblasts and collagenous connective tissue and is infiltrated with a blood vascular network. An indirect immunofluorescence technique and enzyme-linked immunosorbant assay (ELISA) have shown that specific antibodies are elicited by the fish host to these Diphyllobothrium spp. These antibodies have been semi-quantitatively measured by ELISA and correlated with worm burdens in individual fish. |
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Keywords: | Diphyllobothrium immunopathology parasite rainbow trout inflammatory response antibodies |
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