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Liver abscess as the presenting manifestation of chronic granulomatous disease
Authors:Mamishi Setareh  Ahmadi Faezeh  Ahmadi Maedeh  Rezaei Nima
Affiliation:Tehran University of Medical Sciences Infectious Disease Research Center Tehran Iran. smamishi@sina.tums.ac.ir
Abstract:Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disease, affecting phagocytic blood cells, which predispose patients to recurrent infectious complications. Herein, an 11-year-old girl is described who presented with liver abscess at the age of 9 years. Positive dihydrorhodamine (DHR) and nitrobluetetrazolium (NBT) tests confirmed the diagnosis of CGD for the patient. Anti-tuberculosis drugs and parenteral antibiotic therapy were started. Unusual visceral abscess and recurrent infections should be considered as an alarm for primary immunodeficiency diseases, while early diagnosis and appropriate treatment could prevent severe complications and even death in this group of patients.
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