Dopamine- and octopamine-sensitive adenylate cyclase in the brain of adultCulex pipiens mosquitoes |
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Authors: | Stacy Pratt Stephen C Pryor |
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Institution: | 1. Department of Biological Sciences, State University of New York, College at Old Westbury, 11568, Old Westbury, New York, USA
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Abstract: | The effects of dopamine and octopamine on adenylate cyclase activity were studied on the head homogenate of adult Culex pipiens mosquitoes in vitro. Both dopamine and octopamine were shown to increase the cyclic AMP content in the homogenate. The antagonist haloperidol blocked the production of cyclic AMP induced from dopamine but had no effect on the production of cyclic AMP induced by octopamine at the concentrations tested. The opiate agonist etorphine was ineffective at reducing cyclic AMP levels induced by either dopamine or octopamine at the concentrations tested. |
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