Software and methods for oligonucleotide and cDNA array data analysis |
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Authors: | Zapala Matthew A Lockhart Daniel J Pankratz Daniel G Garcia Anthony J Barlow Carrolee Lockhart David J |
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Affiliation: | (1) Laboratory of Genetics, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA; |
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Abstract: | Two HTML-based programs were developed to analyze and filter gene-expression data: 'Bullfrog' for Affymetrix oligonucleotide arrays and 'Spot' for custom cDNA arrays. The programs provide intuitive data-filtering tools through an easy-to-use interface. A background subtraction and normalization program for cDNA arrays was also built that provides an informative summary report with data-quality assessments. These programs are freeware to aid in the analysis of gene-expression results and facilitate the search for genes responsible for interesting biological processes and phenotypes. |
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