Nigro-neostriatal projection |
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| Authors: | Y. Ibata Y. Nojyo T. Matsuura Y. Sano |
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| Affiliation: | (1) Department of Anatomy, Kyoto Prefectural University of Medicine, Kyoto, Japan |
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| Abstract: | Summary The nigro-neostriatal projection was investigated in albino rats and cats with silver impregnation, fluorescence histochemistry and electron microscopy. After unilateral stereotactic electrolysis in the substantia nigra the dopamine fluorescence of ipsilateral neostriatum is markedly reduced. As shown by silver impregnation and electron microscopy, fine terminals and axons are degenerated in the same region. These observations suggest that the nigro-neostriatal pathway may be composed of the fine dopaminergic axons of the nerve cells of unilateral substantia nigra.Dedicated to Professor K. Goerttler on his 75th birthday. — This work was supported by a research grant from the Ministry of Education, Japan. |
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| Keywords: | Substantia nigra and striatum (rat, cat) Stereotactic electrolysis Degeneration Dopamine fluorescence Light and electron microscopy |
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