Antioxidant properties of conjugates of polyethylene glycols containing terpenophenolic fragments |
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| Authors: | I. Yu. Chukicheva M. A. Torlopov E. V. Buravlev O. G. Shevchenko A. V. Kuchin |
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| Affiliation: | 1. Institute of Chemistry, Komi Scientific Center, Ural Branch, Russian Academy of Sciences, ul. Pervomayskaya 48, Syktyvkar, 167982, Russia
2. Institute of Biology, Komi Scientific Center, Ural Branch, Russian Academy of Sciences, Syktyvkar, 167982, Russia
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| Abstract: | A series of water-soluble conjugates has been synthesized from polyethylene glycols of various lengths and 4-bromomethyl-2,6-diisobornylphenol. The membrane protective and antioxidant activities of the synthesized products were evaluated on the model of the H2O2-induced hemolysis of erythrocytes. It was shown that the studied conjugates have a significant antioxidant activity, and a significant membrane protective effect was shown for the conjugates containing 0.2% and 0.8% of the 2,6-diisobornyl-4-methylenephenolic fragments. |
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