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Choroidal metastasis: A case report
Affiliation:1. 1st Department of Ophthalmology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece;2. Clinical Directorate Professional Services, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom;3. St Paul’s Eye Department, Liverpool University Hospitals, Liverpool, United Kingdom;4. Laboratory of Biomathematics, School of Medicine, University of Thessaly, Larissa, Greece;5. Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom;6. Sunderland Eye Infirmary, Sunderland, United Kingdom;7. Bioscience Institute, Newcastle University, Newcastle Upon Tyne, United Kingdom;1. National Eye Institute, National Institutes of Health, Bethesda, Maryland;2. Division of Ophthalmology, Children’s Hospital of Philadelphia, Scheie Eye Institute, Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania;3. Department of Optometry and Visual Science, University of London, London, United Kingdom;4. Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon;5. Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois;6. Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida;7. Retina Consultants, Ltd., Des Plaines, Illinois;8. Department of Ophthalmology, University of Chicago, Chicago, Illinois;9. Associated Retinal Consultants, PC, Royal Oak, Michigan, and Department of Ophthalmology, Oakland University, William Beaumont Hospital School of Medicine, Auburn Hills, Michigan;10. Department of Ophthalmology, China-Japan Friendship Hospital, Beijing, China;11. Ophthalmology Department, Queensland Children’s Hospital, Brisbane, Australia;12. Calgary Retina Consultants, Calgary, Canada;13. Department of Ophthalmology, University of Edinburgh, Edinburgh, United Kingdom;14. Smith-Kettlewell Eye Research Institute, San Francisco, California;15. Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah;16. Department Neuroscience/Ophthalmology, Uppsala University, Uppsala, Sweden;17. Department of Ophthalmology, Kindai University, Osakasayama, Japan;18. Department of Ophthalmology, KYDOFT Foundation, Santiago, Chile;19. A. Gemelli Foundation IRCSS, Department of Ageing and Neuroscience, Catholic University of the Sacred Heart, Rome, Italy;20. Department of Ophthalmology, Justus-Liebig-University Giessen, Giessen, Germany;21. Department of Ophthalmology, Universitaetsklinikum Bonn, Bonn, Germany;22. Retina Department, Asociación para Evitar la Ceguera en México, Mexico City, Mexico;23. Department of Ophthalmology, School of Medicine, Gazi University, Ankara, Turkey;24. Department of Ophthalmology, University of Ilorin, Ilorin, Nigeria;25. Ross Eye Institute, Department of Ophthalmology, University at Buffalo, Buffalo, New York;26. Department of Pediatric Retina and Ocular Oncology, Aravind Eye Hospital, Coimbatore, Tamil Nadu, India;27. Department of Ophthalmology, University Medicine Greifswald, Greifswald, Germany;28. Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina;29. Department of Pediatric Retina, Narayana Nethralaya Eye Institute, Bangalore, Karnataka, India;30. Department of Ophthalmology, University of KwaZulu-Natal, Durban, South Africa;31. Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana;32. Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan, and Chang Gung University, College of Medicine, Taoyuan, Taiwan;33. Department of Ophthalmology, Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China;34. Clinical Research Unit, Fernandes Figueira Institute, FIOCRUZ, Rio de Janeiro, Brazil;1. Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, the Netherlands;2. Department of Internal Medicine, Section Allergy and Clinical Immunology, Erasmus University Medical Center, Rotterdam, the Netherlands;3. Laboratory Medical Immunology, Department of Immunology, Erasmus University Medical Center, Rotterdam, the Netherlands;4. Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia;5. Retina and Uvea Services, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India;6. National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore;7. Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore;8. Ophthalmology and Visual Sciences Academic Clinical Program, Duke NUS University, Singapore;9. Singapore Eye Research Institute, Singapore;10. Moorfields Eye Hospital, London, United Kingdom;1. Sagami Research Laboratories, Wakamoto Pharmaceutical Co., Ltd., Japan;2. Department of Retinal Vascular Biology, Nagoya City University Graduate School of Medical Sciences, Japan;1. The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland;2. Retina Consultants Houston, Houston, Texas;3. Medical Center Ophthalmology Associates, San Antonio, Texas;4. Department of Ophthalmology, California Pacific Medical Center, San Francisco, California;5. Southeast Retina Center, Augusta, Georgia;6. Genentech, Inc., South San Francisco, California
Abstract:Choroidal metastases can display a broad spectrum of clinical signs and symptoms. Due to the fact that they often appear similar to a host of other ocular conditions, the diagnosis may be difficult without a prior history of malignancy. In many instances, ocular symptoms may be the patient's first indication of a problem. A 70-year-old black female presented with multiple, bilateral uveal metastases. In addition to a complete report of this case, a discussion of the incidence, appearance, symptoms, differential diagnoses, etiology and treatment of uveal metastases is provided.
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