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Maculopathy induced by nicotinic acid
Institution:1. Eye Clinic, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University, Naples, Italy;2. Public Health Department, University of Naples Federico II, Naples, Italy;1. From Department of Ophthalmology, Institute of Vision Research, Severance Eye Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea (H.G.K, S.H.B, S.S.K);2. Translational Genome Informatics Laboratory, Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Republic of Korea (H.G.K);3. Department of Ophthalmology, Institute of Vision Research, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea (T.Y.K, J.L, M.K)
Abstract:Nicotinic acid is a commonly used oral medication for the treatment of hyperlipidemia. Numerous systemic and ocular adverse effects have been reported. Cystoid macular edema, although uncommon, has been reported and resolves upon cessation of the medication. What makes this maculopathy unusual is the absence of leakage on fluorescein angiography. A 47-year-old white male presented with the complaint of blurred vision OU for several months. The patient had an extensive medical history, including hyperlipidemia, for which he was taking nicotinic acid. Bilateral cystoid macular edema was diagnosed. Nicotinic acid was discontinued and the patient's vision returned to 20/20 after 2 months.
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