The downstream regulatory sequence of the adenovirus type 2 major late promoter is functionally redundant. |
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Authors: | X C Li W L Huang S J Flint |
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Affiliation: | Department of Molecular Biology, Princeton University, New Jersey 08544-1014. |
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Abstract: | Mutagenesis of promoter sequences and oligonucleotide competition assays have been used to demonstrate the late-phase-specific stimulation of the adenovirus type 2 major late promoter is mediated by functionally redundant elements located between positions +75 and +125. These octamer motif-related sequences are recognized by multiple factors. |
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