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The downstream regulatory sequence of the adenovirus type 2 major late promoter is functionally redundant.
Authors:X C Li   W L Huang     S J Flint
Affiliation:Department of Molecular Biology, Princeton University, New Jersey 08544-1014.
Abstract:Mutagenesis of promoter sequences and oligonucleotide competition assays have been used to demonstrate the late-phase-specific stimulation of the adenovirus type 2 major late promoter is mediated by functionally redundant elements located between positions +75 and +125. These octamer motif-related sequences are recognized by multiple factors.
Keywords:
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