Production and control of freeze-dried Brucella abortus strain 19 vaccine by using cells produced by fermentation units |
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Authors: | M. Zavanella A. Nigrelli F. Ciuchini V. Sala |
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Affiliation: | (1) Istituto Zooprofilattico Sperimentale della Lombardia e del'Emilia, Brescia, Italy;(2) Istituto Superiore di Sanità, Roma, Italy |
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Abstract: | Summary A method of producing freeze-dried Brucella abortus Strain 19 vaccine by using batch cultures on fermentation units is described. Details of the equipment and technique employed, results on microbiological and biological controls are given. |
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