(1) Bioinformatics Centre, School of Biotechnology, Madurai Kamaraj University, Madurai, 625 021, Tamil Nadu, India
Abstract:
Background
Bacterial signal transduction mechanism referred to as a "two component regulatory systems" contributes to the overall adaptability of the bacteria by regulating the gene expression. Osmoregulation is one of the well-studied two component regulatory systems comprising of the sensor, EnvZ and the cognate response regulator, OmpR, which together control the expression of OmpC and OmpF porins in response to the osmolyte concentration.