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Functional Study of the P32T ITPA Variant Associated with Drug Sensitivity in Humans
Authors:Elena I. Stepchenkova  Elena R. Tarakhovskaya  Christin Frahm  Peter D. Simone  Luis A. Marky  Youri I. Pavlov
Affiliation:1 Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, NE 68198-6805, USA
2 Saint Petersburg Branch of Vavilov Institute of General Genetics, Universitetskaya emb. 7/9, St. Petersburg 199034, Russia
3 Department of Plant Physiology and Biochemistry, St. Petersburg State University, Universitetskaya emb. 7/9, St. Petersburg 199034, Russia
4 Drake University, Des Moines, IA 50311, USA
5 Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198-6025, USA
Abstract:
Keywords:ITPase, generic name of enzymes hydrolyzing ITP   ITPA, human ITP pyrophosphatase   IMP, inosine monophosphate   HAP, 6-hydroxylaminopurine   GAPDH, glyceraldehyde-3-phosphate dehydrogenase
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