Comparative genomics of <Emphasis Type="Italic">Thermus thermophilus</Emphasis> and <Emphasis Type="Italic">Deinococcus radiodurans</Emphasis>: divergent routes of adaptation to thermophily and radiation resistance期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Comparative genomics of <Emphasis Type="Italic">Thermus thermophilus</Emphasis> and <Emphasis Type="Italic">Deinococcus radiodurans</Emphasis>: divergent routes of adaptation to thermophily and radiation resistance

Authors:	Marina?V?Omelchenko Yuri?I?Wolf Elena?K?Gaidamakova Vera?Y?Matrosova Alexander?Vasilenko Min?Zhai Michael?J?Daly Eugene?V?Koonin Email author" target="_blank">Kira?S?Makarova Email author

Institution:	(1) Department of Pathology, F.E. Hebert School of Medicine, Uniformed Services University of the Health Sciences, 20814-4799 Bethesda, MD, USA;(2) National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, 20894 Bethesda, MD, USA

Abstract:	Background Thermus thermophilus and Deinococcus radiodurans belong to a distinct bacterial clade but have remarkably different phenotypes. T. thermophilus is a thermophile, which is relatively sensitive to ionizing radiation and desiccation, whereas D. radiodurans is a mesophile, which is highly radiation- and desiccation-resistant. Here we present an in-depth comparison of the genomes of these two related but differently adapted bacteria.

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