Le transit epididymo-deferentiel |
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Authors: | Jean -Pierre Dadoune |
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Institution: | 1. Service de Biologie de la Fertilité et de Cytogénétique, CECOS H?tel-Dieu de Paris, 1, place du Parvis Notre-Dame, 75181, PARIS CEDEX 04
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Abstract: | The epididymis and vas deferens constitute not only a simple conduit for sperm transport but also play an important physiological role in the development of sperm fertilizing ability. The epithelial compartment plays a major functional role in determining the biochemical composition of the luminal fluid in which the spermatozoa undergo a series of structural, biochemical and metabolic changes. During epididymal transit spermatozoa acquire their capacity for motility and also their ability to attach and bind to the zona pellucida and fertilize the oocyte. In man, sperm maturation may occur in the extreme proximal region of the epididymis. The regulation of epididymal and vasa deferential function, as well as sperm maturation, are under androgenic control |
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