| 云南白族人群Y染色体DYF155S1基因座多态性研究 |
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| 引用本文： | 黄艳梅,伍新尧,蔡贵庆,童大跃,区敬华,曾艳红.云南白族人群Y染色体DYF155S1基因座多态性研究[J].人类学学报,2004,23(3):239-247. |
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| 作者姓名： | 黄艳梅 伍新尧 蔡贵庆 童大跃 区敬华 曾艳红 |
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| 作者单位： | 中山大学中山医学院法医系,广州,510089 |
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| 基金项目： | 广东省自然科学基金资助项目(97-128),中山医科大学"211工程"重点学科建设课题基金资助项目(4209008) |
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| 摘 要： | 揭示云南白族136例无关男性个体Y染色体小卫星DYF155S1基因座多态性。用已建立的AmpFLP和MVRPCR方法分析DYF155S1基因座长度多态性、5′端多态性、3′端多态性。DYF155S1基因座具有高度多态性，基因多样性（h）达09996。研究表明将AmpFLP和荧光MVRPCR结合起来更能充分揭示DYF155S1基因座多态性，可为遗传学、人类学及法医学的研究提供有效的工具和基础资料。
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| 关 键 词： | DYF155S1 MVR-PCR Y染色体 人类学 遗传学 |
| 文章编号： | 1000-3193(2004)03-0239-09 |
STUDY ON THE POLYMORPHISM OF DYF155S1 LOCUS, Y-SPECIFIC MINISATELLITE, AMONG BAI POPULATION OF YUNNAN PROVINCE |
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| HUANG Yan-mei,WU Xin-yao,CAI Gui-qing,TONG Da-yue,OU Jing-hua,ZENG Yan-hong.STUDY ON THE POLYMORPHISM OF DYF155S1 LOCUS, Y-SPECIFIC MINISATELLITE, AMONG BAI POPULATION OF YUNNAN PROVINCE[J].Acta Anthropologica Sinica,2004,23(3):239-247. |
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| Authors: | HUANG Yan-mei WU Xin-yao CAI Gui-qing TONG Da-yue OU Jing-hua ZENG Yan-hong |
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| Institution: | HUANG Yan-mei~1,WU Xin-yao~1,CAI Gui-qing~1,TONG Da-yue~1,OU Jing-hua~1,ZENG Yan-hong~1 |
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| Abstract: | This study is to reveal the polymorphism of DYF155S1 locus, Y-specific minisatellite, among 136 cases unrelated male in Bai population of Yunnan Province.The analytical methods include Amp-FLP (Amplified fragment length polymorphism) and MVR-PCR (minisatellite variant repeat by PCR) with type 1-specific primer at 5′end and type 4-specific primer at 3′end. It is found that DYF155S1 locus possesses a high polymorphism and its gene diversity (h) reaches 0. 9996. These results indicated that Amp-FLP in combination with MVR-PCR may reveal fully the polymorphism of DYF155S1 locus and provide a useful tools and more data for the field of human genetics, anthropology and forensic medicine. |
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| Keywords: | DYF155S1 MVR-PCR Y chromosome Anthropology Genetics |
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