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Biological consequences of zinc deficiency in the pathomechanisms of selected diseases |
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| Authors: | Kamil Jurowski Bernadeta Szewczyk Gabriel Nowak Wojciech Piekoszewski |
| Affiliation: | 1. Department of Analytical Chemistry, Faculty of Chemistry, Jagiellonian University, R. Ingardena 3, 30-060, Kraków, Poland 2. Malopolska Centre for Translational Medicine, Faculty of Medicine, Jagiellonian University Collegium Medicum, Kraków, Poland 3. Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland 4. Faculty of Pharmacy, Jagiellonian University Collegium Medicum, Kraków, Poland 5. Laboratory of High Resolution Mass Spectrometry, Regional Laboratory of Physicochemical Analysis and Structural Research, Faculty of Chemistry, Jagiellonian University, Kraków, Poland |
| Abstract: | From many points of view, zinc is one of the most important trace elements in biological systems. Many articles describe the well-known role of this metal in human physiology and pathophysiology, but in the related literature, there is a lack of current and reliable reviews of the role of zinc deficiency in many diseases. In this article, we describe the role of zinc deficiency in the oxidative stress control, immune response, proliferation, and pathogenesis and pathophysiology of selected diseases such as depression, cardiovascular diseases, diabetes mellitus, Alzheimer’s disease, and Wilson’s disease. |
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