| 黑素皮质素受体对动物采食量和能量稳态的调控 |
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| 引用本文： | 蒋思文,彭健,熊远著.黑素皮质素受体对动物采食量和能量稳态的调控[J].遗传,2002,24(2):223-226. |
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| 作者姓名： | 蒋思文 彭健 熊远著 |
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| 作者单位： | 华中农业大学畜牧兽医学院，农业部猪遗传育种重点实验室，武汉，430070
College of Animal Science and Veternary Medicine,Huazhong Agricultural University.The Key Laboratory of Pig Breeding and Genetics,The Ministry of Agriculture.Wuhan 430070,China |
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| 基金项目： | 国家“86 3”( 2 0 0 1AA2 1312 1)，国家重大基础研究项目“973”(G2 0 0 0 0 16 10 5 )，湖北省基金 ( 98J0 2 1)资助 |
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| 摘 要： | 黑素皮质素受体是G-蛋白耦联受体超家族成员。5个黑素皮质素受体基因已经被克隆和鉴定，并有不同的组织分布和生物学功能。本文综述了黑素皮质素受体3和受体4基因调控采食量和能量稳态的研究进展。
Abstract:The melanocortin receptors are members of the super-family of G-protein coupled receptors.To date,five melanocortin receptor genes (MC1R-MC5R) have been cloned and characterized.These receptorsdiffer in their tissue distributions and physiological roles.This review focuses on the roles of MC3R and MC4R in regulation of food intake and energy homeostasis.
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| 关 键 词： | melanocortin receptor 能量稳态 中枢黑素皮质素系统 Key words 黑素皮质素受体 采食量 |
| 文章编号： | 0253-9772(2002)02-0223-04 |
| 修稿时间： | 2001年5月8日 |
Melanocortin Receptor Involvement in the Regulation of Food Intake and Energy Homeostasis |
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| JINAG Si-wen,PENG Jian,XIONG Yuan-zhu.Melanocortin Receptor Involvement in the Regulation of Food Intake and Energy Homeostasis[J].Hereditas,2002,24(2):223-226. |
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| Authors: | JINAG Si-wen PENG Jian XIONG Yuan-zhu |
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| Institution: | College of Animal Science and Veternary Medicine, Huazhong Agricultural University, The Key Laboratory of Pig Breeding and Genetics, The Ministry of Agriculture, Wuhan 430070, China. jiangsiwen@hotmail.com |
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| Abstract: | The melanocortin receptors are members of the super-family of G-protein coupled receptors.To date,five melanocortin receptor genes (MC1R-MC5R) have been cloned and characterized.These receptorsdiffer in their tissue distributions and physiological roles.This review focuses on the roles of MC3R and MC4R in regulation of food intake and energy homeostasis. |
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| Keywords: | melanocortin receptor food intake energy homeostasis the central melanocortin system |
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